Lung xenotransplantation
نویسندگان
چکیده
منابع مشابه
Recommendations of the National Heart, Lung, and Blood Institute Heart and Lung Xenotransplantation Working Group.
The National Heart, Lung, and Blood Institute (NHLBI) recently convened the Heart and Lung Xenotransplantation Working Group to identify hurdles to the clinical application of xenotransplantation, defined as the use of animal organs or tissue for transplantation, and to recommend possible solutions to these problems. The group consisted of experts in xenotransplantation from academia, industry,...
متن کاملClinical xenotransplantation.
Two baboon liver xenografts transplanted to patients with B virus hepatitis supported life for 70 and 26 days but did not function optimally despite minimum or no histopathologic findings of overt humoral or cellular rejection in serial biopsies. However, there was evidence of complement activation in both cases, which in retrospect was thought to explain the unsatisfactory outcome. Strategies ...
متن کاملLiver xenotransplantation.
During the past 30 years orthotopic liver transplantation has become a highly successful form of surgical treatments. The significant advances achieved in this field have led to an increased demand for organs and created a wide gap between organ availability and organ supply. A wider availability of organs for transplantation would allow an expansions rather than a contraction of the indication...
متن کاملKidney Xenotransplantation
Xenotransplantation using pigs as donors offers the possibility of eliminating the chronic shortage of donor kidneys, but there are several obstacles to be overcome before this goal can be achieved. Preclinical studies have shown that, while porcine renal xenografts are broadly compatible physiologically, they provoke a complex rejection process involving preformed and elicited antibodies, heig...
متن کاملXenotransplantation: Today and Tomorrow
Xenotransplantation using pig cells, tissues or organs is at present thought to be the best approach to alleviate the increasing shortage of human tissues and organs for the treatment of tissue and organ failure. This shortage is the reason that approximately 25% of the patients on a waiting list die before they could be treated with an appropriate donor organ. In the US, 30,974 organ transplan...
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ژورنال
عنوان ژورنال: Current Opinion in Organ Transplantation
سال: 2016
ISSN: 1087-2418
DOI: 10.1097/mot.0000000000000311